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Miami to Key West Road Trip: 5 Days Down the Florida Keys

The Overseas Highway, island by island.

A 5-day Miami to Key West road trip down the Overseas Highway — island stops, water views and easy beach days, planned day by day in both directions.

5 days · 336 miMiamiKey LargoKey WestIslamoradaMiami
336 mitotal
7h 20mdriving
$1,104est. budget
Fuel $39Food & stops $425Stays $640Estimates — fuel from your car, stays & stops from your budget tier.
Miami → Key LargoSouth Beach

South Beach

Iconic Art Deco district and beach perfect for morning photos before hitting the road.

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Versailles Restaurant Cuban Cuisine

Legendary Cuban food spot in Miami, a local institution worth a stop before departure.

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68 mi·1h 21m·≈ $8 fuel

John Pennekamp Coral Reef State Park

First underwater park in the US, offering glass-bottom boat tours and snorkeling over vibrant reefs.

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Alabama Jacks

Quirky waterfront seafood shack with conch fritters and Keys character, a classic Overseas Highway stop.

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Overnight in Key Largo

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Key Largo → Key WestSeven Mile Bridge
51 mi·1h 8m·≈ $6 fuel

Seven Mile Bridge

One of the most photographed bridges in the world, spanning turquoise waters between the Keys.

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Bahia Honda State Park

Home to some of the best beaches in the Keys with calm, clear water ideal for swimming and photos.

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Keys Fisheries

Waterfront spot in Marathon famous for its lobster reuben and fresh stone crab.

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48 mi·1h 9m·≈ $6 fuel

Overnight in Key West

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Key West → Key WestMallory Square

Mallory Square

Famous for its nightly sunset celebration with street performers and unbeatable water views.

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Duval Street

The heart of Key West's colorful, lively culture, lined with historic architecture and local shops.

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Blue Heaven

Bohemian courtyard restaurant famous for its Key West shrimp and laid-back island vibe.

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Fort Zachary Taylor Historic State Park Beach

Best beach in Key West for swimming and sunset photos, tucked beside a historic fort.

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Key West Key Lime Pie Co.

A must-try tasting of the town's signature dessert.

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Overnight in Key West

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Key West → IslamoradaTurtle Hospital
48 mi·1h 10m·≈ $6 fuel

Turtle Hospital

Rescue center offering an intimate, meaningful look at sea turtle conservation in the Keys.

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33 mi·43m·≈ $4 fuel

Anne's Beach

Quiet, scenic shallow-water beach great for a relaxed afternoon and photos.

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Lazy Days Restaurant

Beachfront dining in Islamorada known for fresh local seafood and sunset views.

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Overnight in Islamorada

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Islamorada → MiamiJoe's Stone Crab
86 mi·1h 49m·≈ $10 fuel

Joe's Stone Crab

Miami's most iconic seafood institution, the perfect final meal to close out the trip.

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Wynwood Walls

Vibrant outdoor street art museum offering a colorful, photogenic farewell to Miami.

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This route was drafted with AI. Please double-check roads, opening hours and local conditions before you go.

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Miami to Key West Road Trip: 5 Days Down the Florida Keys · Roadtrip Planner